Agilent 6550A iFunnel Accurate-Mass Quadrupole Time-of-Flight (Q-TOF) Mass Spectrometer

Special System Price €  99,500*

*conditions: pre-shipment test at customer site. Installation not included

Pricing & Support

Agilent 6550A iFunnel Accurate-Mass Quadrupole Time-of-Flight (Q-TOF) Mass Spectrometer

MS (Mass Spectrometer)

Agilent 6550A iFunnel Accurate-Mass Quadrupole Time-of-Flight (Q-TOF) Mass Spectrometer features


Specification Description
Sensitivity, MS mode, electrospray on-column, 400 µL/min 1 pg LC/MS injection of reserpine.
Signal-to-noise for the reserpine (M+H)+ at m/z 609.2807 will give 1000:1 RMS
Sensitivity, MS/MS mode, electrospray on-column, 400 µL/min 1 pg LC/MS injection of reserpine. Signal-to-noise for most intense product ions (174, 195,397,448 m/z) will give 3000:1 RMS


4500:1  RMS

Mass resolving power Measured at m/z  2,722 after automatic tuning procedure will be greater than  42,000
Mass accuracy – MS mode, electrospray on-column, 400 µL/min Measured at the (M+H)+ ion of reserpine (m/z 609.2807) using an internal mass reference  – 100 pg LC/MS injection will better than 1 ppm RMS as measured from 10 repeat injections
Mass accuracy – MS/MS mode, , electrospray on-column, 400 µL/min Product ion 397 m/z for reserpine – 100 pg LC/MS injection will be better than 2 ppm RMS on m/z 397 as measured from 10 repeat injections
Dynamic range In-scan dynamic range on co-eluting components will be 5 decades.
Mass range m/z 20 – 10,000
Spectral acquisition rate, MS mode m/z 100 to 3200 in MS mode while maintaining a resolution of 40,000 at m/z  1,522 will be 50 spectra/second
Spectral acquisition rate, MS/MS mode m/z 100 to 3200 in MS/MS mode will be 1 MS and 10 MS/MS spectra/second
Single point of control Single point data system method capability with full control for HPLC system and Q-TOF and communication between the two such that if the LC or MS experiences a “not ready” condition, error, or leak, the system stops injecting the sample
Wide range of optional ionization sources • Electrospray (ESI) (included in package)
• Atmospheric pressure chemical ionization (APCI)
• Atmospheric pressure photoionization (APPI)
• Multimode source (simultaneous ESI and APCI)
• HPLC-Chip/MS interface
• Nanospray source
Transparent introduction of reference masses • Jet Stream focusing technology for superior ion generation and focusing into mass spectrometer
• Built-in calibrant delivery system for automated introduction of reference masses
• Real-time internal reference mass correction for MS and MS/MS operation
Autotune Automated optimization of ion optics and full Q-TOF MS mass axis calibration
Rich data-dependent modes of operation • Precursor selection based upon intensity of n-highest (or n-lowest) or relative or absolute threshold; exclude mass list that now excludes mass range to cover entire isotopic cluster and preferred mass list; dynamic selection of fragmentation energy; preferred charge state; dynamic reduction of transient time based on precursor ion intensity.  
• Intuitive setup of data-dependent experiments
Data mining tools One-button extraction of compound-specific spectral and chromatographic information via ‘Find Compounds’ algorithms
Linked software to enable quick manual review of complex data sets
Software for protein identification
Compound-based data browsing with dynamic links to spectra and chromatograms
Protein database searching software that provides analysis of post-translational modifications, protein ID, denovo sequencing based upon accurate mass MS/MS raw data
Software for verification of recombinant proteins or synthetic peptides Characterization of recombinant proteins including isoforms and post-translational modifications
Software for targeted screening and rapid set up of quantitative methods Screening of compounds using MS/MS without isolation through MS/MS libraries
Molecular profiling tools • Measurement of potentially relevant molecular features from one or more LC/MS analyses (Mass Hunter)
• Differential expression analysis to reveal features that separate one sample set from another (optional Mass Profiler)
• Selection of differential features for subsequent MS/MS identification


Agilent Q-TOF detailed information

Whether you need to identify, screen, profile, or perform quantitation on complex samples, Agilent Q-TOF is ready. When simultaneous speed, sensitivity, accuracy, and dynamic range come together, you get the most information from your samples. The immense detail revealed is harnessed by MassHunter software to provide answers you can trust. The Agilent 6550A iFunnel Q-TOF will help resolving metabolomics, pharmaceutical research, discovery proteomics, food safety, forensics, toxicology, and environmental screening challenges.
Achieve femtogram-level sensitivity–  iFunnel technology increases ion transfer to achieve the lowest detection levels of any high resolution LC/MS instrument

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